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Pfizer, BioNTech COVID-19 Vaccine 90 Percent Effective

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Coronavirus 2

Pfizer and BioNTech COVID-19 Vaccine 90 Percent Effective

In what could be an end to the COVID-19 menace, Pfizer and Germany’s BioNTech latest vaccine has been found to be more than 90 percent effective in coronavirus.

The good news is that the vaccine could be available by the end of the year if authorities approve it.

Pfizer and BioNTech result was the first independent analysis of any COVID-19 vaccine in phase 3 trials— the final stage before commercial licensing. Out of the 43,000 trial participants, the small number who were infected enabled the independent evaluators to calculate the effectiveness after two doses.

“To me, this is the best possible outcome,” Ugur Sahin, co-founder and chief executive of BioNTech told the Financial Times, while Pfizer boss Albert Bourla said it was “a great day for science and humanity”.

The drug is expected to be submitted to authorities for emergency approval in the third week of November, ahead of other vaccine developers. Former vaccine frontrunner Moderna does not expect to have the trial data required to go for approval until November 25, while AstraZeneca’s partnership with the University of Oxford expects results by the end of this year.

Pfizer shares jumped almost 15 per cent in pre-market trading in New York, while Nasdaq-listed BioNTech rose 25 per cent.

The Pfizer results far exceed the US Food and Drug Administration’s criteria for approving a Covid-19 vaccine, which mandates an efficacy of at least 50 per cent in placebo-controlled trials. No vaccine is 100 per cent effective, according to the World Health Organization.

Pfizer and BioNTech said that up to 50m doses of the vaccine — which would be the first vaccine to use novel mRNA technology — could be manufactured this year, and a further 1.3bn doses produced in 2021.

Global equity markets rallied sharply after Pfizer’s announcement, led by travel and leisure companies that have been hit particularly hard by the coronavirus crisis.

British Airways parent IAG soared by a third in London, while Air France KLM jumped 30 per cent in Paris and Ryanair climbed 16 per cent in Dublin. Oil prices, which have been knocked by the pandemic’s effects on demand for fuel, also added to earlier gains. Brent crude, the international standard, was up 8.5 per cent at $42.83 in recent trading.

The US has secured orders for 100m doses of the shot, with an option to acquire another 500m, while the UK has an agreement to procure 30m doses. A deal for the supply of 200m doses to the EU is under negotiation.

Mr Sahin said BioNTech and Pfizer would “use a fair approach” when it came to distributing the first doses of the vaccine, adding that they would prioritise deliveries to countries where it had been approved for use.

“This looks really good,” said Ian Jones, professor of virology at the University of Reading. “Of all the current vaccine currently in development the BioNTech product always looked like the most bang-per-buck as it is entirely focused on the part of the virus that binds to the human cell, the receptor binding domain.”

“The questions around its use were about the ability to manufacture at scale and the possible toxicity associated with a directly injected RNA product. The trial data show excellent results on both of those areas, really impressive protection and no reported adverse events,” he added.

Brendan Wren, professor of vaccinology at the London School of Hygiene and Tropical Medicine, said 90 per cent efficacy was “excellent for a new vaccine”, while adding a note of caution. “It is a case of ‘so far so good’ but more confirmatory safety and efficacy studies are required.”

BioNTech’s Mr Sahin said he expected the vaccine’s immune response to last for “at least one year”, adding that the vaccine-induced antibodies were shown to block about 20 different mutations of Sars-Cov-2. “There’s a very low likelihood that a [mutation of] the virus can overcome the immune response,” he predicted.

CEO/Founder Investors King Ltd, a foreign exchange research analyst, contributing author on New York-based Talk Markets and Investing.com, with over a decade experience in the global financial markets.

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WHO Approves COVID-19 Vaccine Made by Sinopharm in China

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Sinopharm

The World Health Organization said Friday it has approved for emergency use a coronavirus vaccine developed by Chinese state-owned pharmaceutical group Sinopharm.

Beijing’s Covid vaccine is recommended for adults 18 years and up with a two-dose regimen, WHO Director-General Tedros Adhanom Ghebreyesus said at a press briefing.

The new addition to the list of usable vaccine options could hasten efforts to control the spread of Covid-19 and its variant forms, which are driving new infections in many parts of the world.

“Solving the vaccine crisis requires that we pull out all the stops,” Tedros said.

Sinopharm’s shot is the sixth to receive the WHO’s approval for “safety, efficacy and quality,” he said.

“Vaccines remain a vital tool. But right now, the volume and distribution of vaccines are insufficient to end the pandemic, without the sustained and tailored application of public health measures that we know work,” Tedros said.

“The pandemic has shown that when health is at risk, everything is at risk. But when health is protected and promoted, individuals, families, communities, economies, and nations can thrive,” he said.

The state-owned drugmaker’s two-dose Covid shot has already been approved for emergency use in China, the United Arab Emirates, and Bahrain.

Another Chinese shot, made by the private company Sinovac, has not yet been approved by the WHO.

In the U.S., vaccines developed by Pfizer-BioNTech, Moderna, and Johnson & Johnson have received emergency use authorizations by the Food and Drug Administration.

The WHO has granted emergency validation for those three shots, as well as for vaccines produced by AstraZeneca-SK BIO and the Serum Institute of India.

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Crypto.com Becomes Official Cryptocurrency & NFT Sponsor Of The 2021 Coppa Italia

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Lega Serie A and Crypto.com announced that they have reached an important partnership agreement on the occasion of the 2021 Coppa Italia Final, which will see Atalanta challenge Juventus on 19th May at the Mapei Stadium in Reggio Emilia.

Lega Serie A is proud to be the first football league to sign a partnership agreement with a cryptocurrency and NFT platform. The partnership, which begins with the Coppa Italia Final is expected to extend long into the future. To commemorate the first time Atalanta and Juventus meet at the Coppa Italia Final, a special NFT collection will be made available including the official trophy, match highlights, and more.

With the fastest growing crypto app and over 10 million users worldwide, Crypto.com is proud to be Lega Serie A’s first cryptocurrency partner. Together the two organizations will create new experiences for football fans in Italy and beyond, starting with special NFT collectibles available exclusively at Crypto.com/NFT.

“We are extremely proud to announce this prestigious partnership with Crypto.com, a leading company in the world of cryptocurrencies and NFTs – said Luigi De Siervo, CEO of Lega Serie A – We are the first football league in the world to sign an agreement in this new market which is extremely innovative and relevant not only for sports fans, where other world-class leagues such as the NBA have been operating in recent months. In this way Lega Serie A aims to expand its target audience and continues the international growth of the brand, always looking to the future and innovation. The Coppa Italia Final will be an expression of these values and will offer millions of fans around the world an exciting experience not only on the pitch but also before and after the game, thanks to the many commercial and marketing initiatives that we will organize with our partners”.

“We are proud to collaborate with an exceptional partner such as Lega Serie A, the latest in an exciting roadmap of sports partnerships we’ll soon be announcing,” said Kris Marszalek, co-founder and CEO of Crypto.com. “It’s a unique opportunity to support the world’s most popular sport during the historic match between Atalanta and Juventus, surely to be watched by football fans world-wide. Through our partnership, we will bring together the best of blockchain technology and football by co-creating NFTs sure to become instant classics and highly coveted collectibles.”

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Pastor Adeboye’s Son Dare Dies At 42

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Dare Adeboye

Pastor Dare Adeboye, the son of the General Overseer of the Redeemed Christian Church of God Worldwide, Enoch Adeboye, is dead.

The media gathered that the 42-year-old, who is the third son of the revered cleric, died in his sleep on Wednesday in Eket, Akwa Ibom State, where he was based with his family.

Our correspondent gathered from reliable sources in the church that the deceased, who was the Assistant Pastor in charge of Region (Youth) 35, had ministered the previous day.

He was said to have retired to his bed and did not wake up.

His wife, Temiloluwa, was said to have raised the alarm.

“He was not sick and did not complain of anything before the incident. Pastors in the church were summoned to pray for him, all to no avail,” a source added.

The Head of Media and Public Relations, RCCG, Pastor Olaitan Olubiyi, however, confirmed the tragedy on Thursday morning.

He said, “It is true. The incident happened in Eket where he was based. I don’t have the details for now. Maybe before the end of today, we will issue a statement.”

Dare would have been 43 years old next month, June.

Last year, on his 42nd birth, his dad, Adeboye on a social media post described him as his first miracle child.

He wrote on his Facebook page,
“Our first miracle child. We pray that God will keep his miraculous working power in your life and all those who need a miracle today, will use you as a point of contact for their own in JESUS name. (Amen) love from Dad, Mom and the whole Adeboye dynasty.”

Dare was happily married with children.

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